El Premio Primetime Emmy a la Mejor Serie Dramática es uno de los principales galardonados presentados por la Academia de Artes y Ciencias de la Televisión en reconocimiento a la excelencia en la programación televisiva estadounidense en el horario estelar o de máxima audiencia.
| Año | Ganadores del Premio Primetime Emmy a la Mejor Serie Dramática |
| 2025 | TBA |
| 2024 | Shogun (FX) |
| 2023 | Succession (HBO) |
| 2022 | Succession (HBO) |
| 2021 | The Crown (Netflix) |
| 2020 | Succession (HBO) |
| 2019 | Game of Thrones (HBO) |
| 2018 | Game of Thrones (HBO) |
| 2017 | The Handmaid’s Tale (Hulu) |
| 2016 | Game of Thrones (HBO) |
| 2015 | Game of Thrones (HBO) |
| 2014 | Breaking Bad (AMC) |
| 2013 | Breaking Bad (AMC) |
| 2012 | Homeland (Showtime) |
| 2011 | Mad Men (AMC) |
| 2010 | Mad Men (AMC) |
| 2009 | Mad Men (AMC) |
| 2008 | Mad Men (AMC) |
| 2007 | The Sopranos (HBO) |
| 2006 | 24 (FOX) |
| 2005 | Lost (ABC) |
| 2004 | The Sopranos (HBO) |
| 2003 | The West Wing (NBC) |
| 2002 | The West Wing (NBC) |
| 2001 | The West Wing (NBC) |
| 2000 | The West Wing (NBC) |
| 1999 | The Practice (ABC) |
| 1998 | The Practice (ABC) |
| 1997 | Law & Order (NBC) |
| 1996 | ER (NBC) |
| 1995 | NYPD Blue (ABC) |
| 1994 | Picket Fences (CBS) |
| 1993 | Picket Fences (CBS) |
| 1992 | Northern Exposure (CBS) |
| 1991 | L.A. Law (NBC) |
| 1990 | L.A. Law (NBC) |
| 1989 | L.A. Law (NBC) |
| 1988 | Thirtysomething (ABC) |
| 1987 | L.A. Law (NBC) |
| 1986 | Cagney & Lacey (CBS) |
| 1985 | Cagney & Lacey (CBS) |
| 1984 | Hill Street Blues (NBC) |
| 1983 | Hill Street Blues (NBC) |
| 1982 | Hill Street Blues (NBC) |
| 1981 | Hill Street Blues (NBC) |
| 1980 | Lou Grant (CBS) |
| 1979 | Lou Grant (CBS) |
| 1978 | The Rockford Files (NBC) |
| 1977 | Upstairs, Downstairs (PBS) |
| 1976 | Police Story (NBC) |
| 1975 | Upstairs, Downstairs (PBS) |
| 1974 | Upstairs, Downstairs (PBS) |
| 1973 | The Waltons (CBS) |
| 1972 | Elizabeth R (PBS) |
| 1971 | The Bold Ones: The Senator (NBC) |
| 1970 | Marcus Welby MD (ABC) |
| 1969 | NET Playhouse (NET) |
| 1968 | Mission: Impossible (CBS) |
| 1967 | Mission: Impossible (CBS) |
| 1966 | The Fugitive (ABC) |
| 1965 | N/A |
| 1964 | The Defenders (CBS) |
| 1963 | The Defenders (CBS) |
| 1962 | The Defenders (CBS) |
| 1961 | Hallmark Hall of Fame: Macbeth (NBC) |
| 1960 | Playhouse 90 (CBS) |
| 1959 | Alcoa-Goodyear Theater (NBC) & Playhouse 90 (CBS) & Maverick (ABC) |
| 1958 | Gunsmoke (CBS) & Playhouse 90 (CBS) |
| 1957 | The Phil Silvers Show (CBS) & Caesar’s Hour (NBC) |
| 1956 | The Producers’ Showcase (NBC) & Disneyland (ABC) |
| 1955 | The United States Steel Hour (ABC) & Dragnet (NBC) |
| 1954 | The United States Steel Hour (ABC) & Dragnet (NBC) |
| 1953 | Robert Montgomery Presents (NBC) & Dragnet (NBC) |
| 1952 | Studio One (CBS) |